Molecular analysis of the Neurospora qa-1 regulatory region indicates that two interacting genes control qa gene expression.
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چکیده
منابع مشابه
Molecular analysis of the Neurospora qa-1 regulatory region indicates that two interacting genes control qa gene expression.
The qa-1 regulatory region controls the expression of the three structural genes required for the early reactions in quinic acid catabolism in Neurospora crassa. Genetic analysis previously identified two types of noninducible qa-1 mutants, qa-1S and qa-1F, which mapped in separate non-overlapping regions. These mutations were originally interpreted as defining separate domains of a single regu...
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An ensemble of genetic networks that describe how the model fungal system, Neurospora crassa, utilizes quinic acid (QA) as a sole carbon source has been identified previously. A genetic network for QA metabolism involves the genes, qa-1F and qa-1S, that encode a transcriptional activator and repressor, respectively and structural genes, qa-2, qa-3, qa-4, qa-x, and qa-y. By a series of 4 separat...
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In Neurospora crassa, the enzyme quinate (shikimate) dehydrogenase catalyzes the first reaction in the inducible quinic acid catabolic pathway and is encoded in the qa-3 gene of the qa cluster. In this cluster, the order of genes has been established as qa-1 qa-3 qa-4 qa-2. Amino-terminal sequences have been determined for purified quinate dehydrogenase from wild type and from UV-induced revert...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1984
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.81.4.1174